Intranasal Low-Dose Naltrexone Against Opioid Side Effects: A Preclinical Study

• Main Authors: Laura Micheli (Author), Lorenzo Di Cesare Mannelli (Author), Elena Lucarini (Author), Carmen Parisio (Author), Alessandra Toti (Author), Bruno Fiorentino (Author), Maria Adele Rigamonti (Author), Laura Calosi (Author), Carla Ghelardini (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Opioids are broad spectrum analgesics that are an integral part of the therapeutic armamentarium to combat pain in the clinical practice. Unfortunately, together with analgesia, a number of adverse effects can occur such as nausea, vomiting, constipation, gastrointestinal alterations and cognitive i...