The applications of machine learning to predict the forming of chemically stable amorphous solid dispersions prepared by hot-melt extrusion

Amorphous solid dispersion (ASD) is one of the most important strategies to improve the solubility and dissolution rate of poorly water-soluble drugs. As a widely used technique to prepare ASDs, hot-melt extrusion (HME) provides various benefits, including a solvent-free process, continuous manufact...

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Main Authors: Junhuang Jiang (Author), Anqi Lu (Author), Xiangyu Ma (Author), Defang Ouyang (Author), Robert O. Williams, III (Author)
Format: Book
Published: Elsevier, 2023-12-01T00:00:00Z.
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