Acute cold hypersensitivity characteristically induced by oxaliplatin is caused by the enhanced responsiveness of TRPA1 in mice

• Main Authors: Zhao Meng (Author), Isami Kouichi (Author), Nakamura Saki (Author), Shirakawa Hisashi (Author), Nakagawa Takayuki (Author), Kaneko Shuji (Author)
• Format: Book
• Published: SAGE Publishing, 2012-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Oxaliplatin, a platinum-based chemotherapeutic agent, causes an unusual acute peripheral neuropathy. Oxaliplatin-induced acute peripheral neuropathy appears in almost all patients rapidly after infusion, and is triggered or exacerbat...