Acute cold hypersensitivity characteristically induced by oxaliplatin is caused by the enhanced responsiveness of TRPA1 in mice

• Glavni autori: Zhao Meng (Autor), Isami Kouichi (Autor), Nakamura Saki (Autor), Shirakawa Hisashi (Autor), Nakagawa Takayuki (Autor), Kaneko Shuji (Autor)
• Format: Knjiga
• Izdano: SAGE Publishing, 2012-07-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Oxaliplatin, a platinum-based chemotherapeutic agent, causes an unusual acute peripheral neuropathy. Oxaliplatin-induced acute peripheral neuropathy appears in almost all patients rapidly after infusion, and is triggered or exacerbat...