High Frequency of CYP2A6*4, CYP2A6*7, and CYP2A6*9 Alleles Detected Among Patients with Type 2 Diabetic: Genetic Study in The Private Hospital in Yogyakarta

• Main Authors: Christine Patramurti (Author), Dita Maria Virginia (Author), Fenty Fenty (Author), Christianus Heru Setiawan (Author), Jeffry Julianus (Author), Phebe Hendra (Author), Nicholas Adi Perdana Susanto (Author)
• Format: Book
• Published: Universitas Sanata Dharma, 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Smoking is a risk factor for type 2 diabetic (T2DM), since the nicotine in cigarettes can cause insulin resistance and increase lipolysis. Both of these can worsen the condition of patients with T2DM and increase treatment failure. Nicotine is metabolized to cotinine by the CYP2A6 enzyme encoded by...