Polyhydroxyalkanoate/Antifungal Polyene Formulations with Monomeric Hydroxyalkanoic Acids for Improved Antifungal Efficiency

• Autori principali: Marina Pekmezovic (Autore), Melina Kalagasidis Krusic (Autore), Ivana Malagurski (Autore), Jelena Milovanovic (Autore), Karolina Stępień (Autore), Maciej Guzik (Autore), Romina Charifou (Autore), Ramesh Babu (Autore), Kevin O'Connor (Autore), Jasmina Nikodinovic-Runic (Autore)
• Natura: Libro
• Pubblicazione: MDPI AG, 2021-06-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Novel biodegradable and biocompatible formulations of "old" but "gold" drugs such as nystatin (Nys) and amphotericin B (AmB) were made using a biopolymer as a matrix. Medium chain length polyhydroxyalkanoates (mcl-PHA) were used to formulate both polyenes (Nys and AmB) in the for...