Pregnancy Recommendations Solely Based on Preclinical Evidence Should Be Integrated with Real-World Evidence: A Disproportionality Analysis of Certolizumab and Other TNF-Alpha Inhibitors Used in Pregnant Patients with Psoriasis

• Main Authors: Mario Gaio (Author), Maria Giovanna Vastarella (Author), Maria Giuseppa Sullo (Author), Cristina Scavone (Author), Consiglia Riccardi (Author), Maria Rosaria Campitiello (Author), Liberata Sportiello (Author), Concetta Rafaniello (Author)
• Format: Book
• Published: MDPI AG, 2024-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Treatment for pregnant women with psoriasis is limited by the lack of information typically related to clinical trials. While anti-tumor necrosis factor (TNF) drugs offer therapeutic benefits, their safety during pregnancy is a concern. Notably, certolizumab is comparatively safer than adalimumab, e...