Analgesic effects of oral Yokukansan on acute postoperative pain and involvement of the serotonin nervous system: a mouse model study

• Main Authors: Shuichiro Kurita (Author), Mika Sasaki (Author), Moegi Tanaka (Author), Yoshinori Kuwabara (Author), Yukino Ogasawara (Author), Hiroshi Baba (Author), Yoshinori Kamiya (Author)
• Format: Book
• Published: BMC, 2024-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Yokukansan, a traditional Japanese medicine (Kampo), has been widely used to treat neurosis, dementia, and chronic pain. Previous in vitro studies have suggested that Yokukansan acts as a partial agonist of the 5-HT1A receptor, resulting in amelioration of chronic pain through in...