Chronic Ethanol Feeding Modulates Inflammatory Mediators, Activation of Nuclear Factor-κB, and Responsiveness to Endotoxin in Murine Kupffer Cells and Circulating Leukocytes

• Hauptverfasser: Miriam Maraslioglu (Verfasst von), Elsie Oppermann (Verfasst von), Carolin Blattner (Verfasst von), Roxane Weber (Verfasst von), Dirk Henrich (Verfasst von), Christian Jobin (Verfasst von), Elke Schleucher (Verfasst von), Ingo Marzi (Verfasst von), Mark Lehnert (Verfasst von)
• Format: Buch
• Veröffentlicht: Hindawi Limited, 2014-01-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

Chronic ethanol abuse is known to increase susceptibility to infections after injury, in part, by modification of macrophage function. Several intracellular signalling mechanisms are involved in the initiation of inflammatory responses, including the nuclear factor-κB (NF-κB) pathway. In this study,...