Pharmacological study on the enhancing effects of U46619 on guinea pig urinary bladder smooth muscle contraction induced by acetylcholine and α,β-methylene ATP and the possible involvement of protein kinase C

• Main Authors: Guanghan Ou (Author), Akane Komura (Author), Misaki Hojo (Author), Rina Kato (Author), Masahiro Ikeda (Author), Miki Fujisawa (Author), Keyue Xu (Author), Kento Yoshioka (Author), Keisuke Obara (Author), Yoshio Tanaka (Author)
• Format: Book
• Published: Elsevier, 2023-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

We examined whether U46619 (a prostanoid TP receptor agonist) could enhance the contractions of guinea pig urinary bladder smooth muscle (UBSM) in response to acetylcholine (ACh) and an ATP analog (α,β-methylene ATP (αβ-MeATP)) through stimulation of the UBSM TP receptor and whether protein kinase C...