Preclinical Pharmacokinetics and Biodistribution of Anticancer Dinuclear Palladium(II)-Spermine Complex (Pd₂Spm) in Mice

• Hoofdauteurs: Martin Vojtek (Auteur), Salomé Gonçalves-Monteiro (Auteur), Edgar Pinto (Auteur), Sára Kalivodová (Auteur), Agostinho Almeida (Auteur), Maria P. M. Marques (Auteur), Ana L. M. Batista de Carvalho (Auteur), Clara B. Martins (Auteur), Helder Mota-Filipe (Auteur), Isabel M. P. L. V. O. Ferreira (Auteur), Carmen Diniz (Auteur)
• Formaat: Boek
• Gepubliceerd in: MDPI AG, 2021-02-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Palladium-based compounds are regarded as potential analogs to platinum anticancer drugs with improved properties. The present study assessed the pharmacokinetics and biodistribution of a dinuclear palladium(II)-spermine chelate (Pd₂Spm), which has previously been shown to pos...