Is the Association Between TNF-α-308 A Allele and DMT1 Independent of HLA-DRB1, DQB1 Alleles?

• Principais autores: Grazyna Deja (Autor), Przemyslawa Jarosz-Chobot (Autor), Joanna Polanska (Autor), Urszula Siekiera (Autor), Ewa Malecka-Tendera (Autor)
• Formato: Livro
• Publicado em: Hindawi Limited, 2006-01-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

The aim of the study was to assess chosen factors of genetic susceptibility to DMT1: DRB1, DQB1, and TNF-α polymorphisms-308 (G/A) in children with DMT1 and their up-to-now healthy siblings. Then we tested whether the association between TNF-α genes and DMT1 is independent of HLA. 87 diabetic childr...