Site-specific PEGylation of lidamycin and its antitumor activity

In this study, N-terminal site-specific mono-PEGylation of the recombinant lidamycin apoprotein (rLDP) of lidamycin (LDM) was prepared using a polyethyleneglycol (PEG) derivative (Mw 20 kDa) through a reactive terminal aldehyde group under weak acidic conditions (pH 5.5). The biochemical properties...

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Main Authors: Liang Li (Author), Boyang Shang (Author), Lei Hu (Author), Rongguang Shao (Author), Yongsu Zhen (Author)
Format: Book
Published: Elsevier, 2015-05-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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