Non‐synonymous alterations in AKR7A3 and ABCA6 correlate with bleeding in aged patients treated with rivaroxaban

• Main Authors: Ming Zhao (Author), Qiang Zhang (Author), Xizi Wang (Author), Qianqian Zhang (Author), Conghui Tian (Author), Rongrong Li (Author), Xiaodong Jia (Author), Mingliang Gu (Author), Liping Yang (Author)
• Format: Book
• Published: Wiley, 2022-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Rivaroxaban is an oral anticoagulant that inhibits thrombin and blocks coagulation cascade through directly inactivating factors Xa. Despite rivaroxaban is widely used for prevention and treatment of venous thrombosis, and its common adverse reactions have been reported, including abnormal...