COX-2 in Cancer: Gordian knot or Achilles heel?

• Main Authors: Ioannis eStasinopoulos (Author), Tariq eShah (Author), Marie-France ePenet (Author), Balaji eKrishnamachary (Author), Zaver M. Bhujwalla (Author)
• Format: Book
• Published: Frontiers Media S.A., 2013-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The networks of blood and lymphatic vessels and of the extracellular matrix and their cellular and structural components, that are collectively termed the tumor microenvironment, are frequently co-opted and shaped by cancer cells to survive, invade and form distant metastasis. With an enviable capac...