Mathematical Modeling of Hydroxyurea Therapy in Individuals with Sickle Cell Disease

• Asıl Yazarlar: Akancha Pandey (Yazar), Jeremie H. Estepp (Yazar), Rubesh Raja (Yazar), Guolian Kang (Yazar), Doraiswami Ramkrishna (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: MDPI AG, 2022-05-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Sickle cell disease (SCD) is a chronic hemolytic anemia affecting millions worldwide with acute and chronic clinical manifestations and early mortality. While hydroxyurea (HU) and other treatment strategies managed to ameliorate disease severity, high inter-individual variability in clinical respons...