Effects of Azimilide on the Muscarinic Acetylcholine Receptor-Operated K+ Current and Experimental Atrial Fibrillation in Guinea-Pig Hearts

• Main Authors: Atsushi Nishida (Author), Yoshie Reien (Author), Takehiko Ogura (Author), Hiroko Uemura (Author), Masaji Tamagawa (Author), Hideo Yabana (Author), Haruaki Nakaya (Author)
• Format: Book
• Published: Elsevier, 2007-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Effects of azimilide, a class III antiarrhythmic drug, on the acetylcholine (ACh) receptor-operated K+ current (IK.ACh) and the delayed rectifier K+ current (IK) were examined in guinea-pig atrial cells using patch-clamp techniques. Effects of azimilide on experimental atrial fibrillation (AF) were...