Sensory neuron cultures derived from adult db/db mice as a simplified model to study type-2 diabetes-associated axonal regeneration defects

• Main Authors: Cristian De Gregorio (Author), Fernando Ezquer (Author)
• Format: Bog
• Udgivet: The Company of Biologists, 2021-01-01T00:00:00Z.
• Fag: article
• Online adgang: Connect to this object online.

Diabetic neuropathy (DN) is an early common complication of diabetes mellitus (DM), leading to chronic pain, sensory loss and muscle atrophy. Owing to its multifactorial etiology, neuron in vitro cultures have been proposed as simplified systems for DN studies. However, the most used models currentl...