Downregulation of HNRNPA1 induced neoantigen generation via regulating alternative splicing

• Main Authors: Yaoqi Sun (Author), Bing Xiong (Author), Xueqian Shuai (Author), Jiale Li (Author), Chunyan Wang (Author), Jing Guo (Author), Zhongping Cheng (Author), Shupeng Liu (Author)
• Format: Book
• Published: BMC, 2024-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Immunotherapies effectively treat human malignancies, but the low response and resistance are major obstacles. Neoantigen is an emerging target for tumor immunotherapy that can enhance anti-tumor immunity and improve immunotherapy. Aberrant alternative splicing is an important so...