Multiplexed digital mRNA profiling of the inflammatory response in the West Nile Swiss Webster mouse model.

• Main Authors: José Peña (Author), Jessica A Plante (Author), Alda Celena Carillo (Author), Kimberly K Roberts (Author), Jennifer K Smith (Author), Terry L Juelich (Author), David W C Beasley (Author), Alexander N Freiberg (Author), Montiago X Labute (Author), Pejman Naraghi-Arani (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2014-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The ability to track changes in gene expression following viral infection is paramount to understanding viral pathogenesis. This study was undertaken to evaluate the nCounter, a high throughput digital gene expression system, as a means to better understand West Nile virus (WNV) dissemination and th...