Cluster Gauss‐Newton method for a quick approximation of profile likelihood: With application to physiologically‐based pharmacokinetic models
Abstract Physiologically‐based pharmacokinetic (PBPK) models can be challenging to work with because they can have too many parameters to identify from observable data. The profile likelihood method can help solve this issue by determining parameter identifiability and confidence intervals, but it i...
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Wiley,
2024-01-01T00:00:00Z.
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