PPAR Gamma-Regulated MicroRNA 199a-5p Underlies Bone Marrow Adiposity in Aplastic Anemia

• Main Authors: Xianning Zhang (Author), Lulu Liu (Author), Cuiyun Dou (Author), Panpan Cheng (Author), Lei Liu (Author), Haihui Liu (Author), Saisai Ren (Author), Cuiling Wang (Author), Shu Jia (Author), Lulu Chen (Author), Hao Zhang (Author), Mingtai Chen (Author)
• Format: Book
• Published: Elsevier, 2019-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Increased propensity of bone marrow-derived mesenchymal stem cells (BM-MSCs) toward adipogenic differentiation has been implicated in the fatty bone marrow and defective hematopoiesis of aplastic anemia (AA). However, the underlying molecular mechanism remains to be investigated. In this study, we f...