Expression of TNF-α and Related Signaling Molecules in the Peripheral Blood Mononuclear Cells of Rheumatoid Arthritis Patients

• Main Authors: Sunil Kumar Raghav (Author), Bhawna Gupta (Author), Charu Agrawal (Author), Ved P. Chaturvedi (Author), Hasi R. Das (Author)
• Format: Book
• Published: Hindawi Limited, 2006-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

We examined the role of tumor necrosis factor (TNF-α) and its related signaling intermediates leading to apoptosis/proliferation in the peripheral blood mononuclear cells (PBMCs) of RA patients. The constitutive expression of mRNA for TNF-α receptors (TNFR-I and TNFR-II) and the adapter molecules, s...