Intrapulmonary and Systemic Pharmacokinetics of Colistin Following Nebulization of Low-Dose Colistimethate Sodium in Patients with Ventilator-Associated Pneumonia Caused by Carbapenem-Resistant <i>Acinetobacter baumannii</i>

• Main Authors: Dong-Hwan Lee (Author), Shin-Young Kim (Author), Yong-Kyun Kim (Author), So-Young Jung (Author), Ji-Hoon Jang (Author), Hang-Jea Jang (Author), Jae-Ha Lee (Author)
• Format: Book
• Published: MDPI AG, 2024-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Colistimethate sodium (CMS) nebulization is associated with reduced systemic toxicity compared to intravenous injection, with potentially enhanced clinical efficacy. This study aimed to assess the pharmacokinetic (PK) properties of colistin during low-dose CMS nebulization in patients with ventilato...