The tumor suppressor 5A2, a synthetic miR-7-5p mimic, targets oncogenic and metabolic pathways, as revealed by transcriptome-wide analysis

• Main Authors: Marion T. J. van den Bosch (Author), Bryony J. Telford (Author), Sanaz Yahyanejad (Author), Thijs de Gunst (Author), Harm C. den Boer (Author), Rogier M. Vos (Author), Chantal L. Duurland (Author), Rianne Biemans (Author), Ludwig J. Dubois (Author), Laurens A. H. van Pinxteren (Author), Roel Q. J. Schaapveld (Author), Michel Janicot (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

As cancer is a multifactorial disease, the multimodal action of microRNAs makes them an attractive tool for novel therapeutic approaches. The tumor suppressive miR-7-5p has been shown to act on many aspects of oncogenesis, including cell proliferation, migration and angiogenesis, by targeting a spec...