Dissecting the Role of SMYD2 and Its Inhibitor (LLY-507) in the Treatment of Chemically Induced Non-Small Cell Lung Cancer (NSCLC) by Using Fe₃O₄ Nanoparticles Drug Delivery System

• Autores principales: Aasma Munawwar (Autor), Amna Sajjad (Autor), Azhar Rasul (Autor), Mehran Sattar (Autor), Farhat Jabeen (Autor)
• Formato: Libro
• Publicado: MDPI AG, 2023-07-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

Cancer therapies based on nanoparticles with a loaded drug can overcome the problem of the drug's toxic effects in the traditional chemotherapeutic approach. In this study, we loaded LLY-507, a potent inhibitor of SMYD2, a methyltransferase enzyme, on iron oxide nanoparticles (IONPs). The prepa...