Antisense 2'-Deoxy, 2'-Fluoroarabino Nucleic Acid (2'F-ANA) Oligonucleotides: In Vitro Gymnotic Silencers of Gene Expression Whose Potency Is Enhanced by Fatty Acids

Gymnosis is the process of the delivery of antisense oligodeoxynucleotides to cells, in the absence of any carriers or conjugation, that produces sequence-specific gene silencing. While gymnosis was originally demonstrated using locked nucleic acid (LNA) gapmers, 2'-deoxy-2'fluoroarabino n...

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Bibliographic Details
Main Authors: Naira Souleimanian (Author), Glen F Deleavey (Author), Harris Soifer (Author), Sijian Wang (Author), Katrin Tiemann (Author), Masad J Damha (Author), Cy A Stein (Author)
Format: Book
Published: Elsevier, 2012-01-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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