Correlation between Antimicrobial Resistance and the Hospital-Wide Diverse Use of Broad-Spectrum Antibiotics by the Antimicrobial Stewardship Program in Japan

• Main Authors: Takashi Ueda (Author), Yoshio Takesue (Author), Kazuhiko Nakajima (Author), Kaoru Ichiki (Author), Kaori Ishikawa (Author), Kumiko Yamada (Author), Toshie Tsuchida (Author), Naruhito Otani (Author), Yoshiko Takahashi (Author), Mika Ishihara (Author), Shingo Takubo (Author), Kosuke Iijima (Author), Hiroki Ikeuchi (Author), Motoi Uchino (Author), Takeshi Kimura (Author)
• Format: Book
• Published: MDPI AG, 2023-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Increased antibiotic use and antibiotic homogeneity cause selective pressure. This study investigated the correlation between antibiotic diversity and antimicrobial resistance (AMR) in Gram-negative organisms. The days of therapy/100 patient-days (DOT) for four broad-spectrum antibiotic classes were...