Doxorubicin-Loaded Delta Inulin Conjugates for Controlled and Targeted Drug Delivery: Development, Characterization, and In Vitro Evaluation

• Autores principales: Lixin Wang (Autor), Yunmei Song (Autor), Ankit Parikh (Autor), Paul Joyce (Autor), Rosa Chung (Autor), Liang Liu (Autor), Franklin Afinjuomo (Autor), John D. Hayball (Autor), Nikolai Petrovsky (Autor), Thomas G. Barclay (Autor), Sanjay Garg (Autor)
• Formato: Libro
• Publicado: MDPI AG, 2019-11-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

Delta inulin, also known as microparticulate inulin (MPI), was modified by covalently attaching doxorubicin to its nanostructured surface for use as a targeted drug delivery vehicle. MPI is readily endocytosed by monocytes, macrophages, and dendritic cells and in this study, we sought to utilize thi...