Prothrombotic Effect of Anti-beta-2 Glycoprotein-1 Antibodies on the Expression of Tissue Factor, Thrombomodulin, and Plasminogen Activator Inhibitor-1 in Endothelial Cells

• Main Authors: Rikarni Rikarni (Author), Rahajuningsih Dharma (Author), Tambunan L Tambunan (Author), Harry Isbagyo (Author), Beti E. E Dewi (Author), Nuzirwan Acang (Author), Rianto Setiabudy (Author), Adi K Aman (Author)
• Format: Book
• Published: Interna Publishing, 2015-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Aim: to analyse the effects of immunoglobulin (Ig)G and IgM anti-beta-2 glycoprotein-1 (anti-β2GP1) on the expression of tissue factor (TF), thrombomodulin (TM), and plasminogen activator inhibitor-1(PAI-1) of endothelial cells in the messenger RNA level. Methods: laboratory experimental study in hu...