Tight Junction Modulating Bioprobes for Drug Delivery System to the Brain: A Review

• Main Authors: Keisuke Tachibana (Author), Yumi Iwashita (Author), Erika Wakayama (Author), Itsuki Nishino (Author), Taiki Nishikaji (Author), Masuo Kondoh (Author)
• Format: Book
• Published: MDPI AG, 2020-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The blood-brain barrier (BBB), which is composed of endothelial cells, pericytes, astrocytes, and neurons, separates the brain extracellular fluid from the circulating blood, and maintains the homeostasis of the central nervous system (CNS). The BBB endothelial cells have well-developed tight juncti...