Genetic and environmental circadian disruption induce weight gain through changes in the gut microbiome

• Hoofdauteurs: Baraa Altaha (Auteur), Marjolein Heddes (Auteur), Violetta Pilorz (Auteur), Yunhui Niu (Auteur), Elizaveta Gorbunova (Auteur), Michael Gigl (Auteur), Karin Kleigrewe (Auteur), Henrik Oster (Auteur), Dirk Haller (Auteur), Silke Kiessling (Auteur)
• Formaat: Boek
• Gepubliceerd in: Elsevier, 2022-12-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Objective: Internal clocks time behavior and physiology, including the gut microbiome, in a circadian (∼24 h) manner. Mismatch between internal and external time, e.g. during shift work, disrupts circadian system coordination promoting the development of obesity and type 2 diabetes (T2D). Conversely...