Genetic and environmental circadian disruption induce weight gain through changes in the gut microbiome

• Päätekijät: Baraa Altaha (Tekijä), Marjolein Heddes (Tekijä), Violetta Pilorz (Tekijä), Yunhui Niu (Tekijä), Elizaveta Gorbunova (Tekijä), Michael Gigl (Tekijä), Karin Kleigrewe (Tekijä), Henrik Oster (Tekijä), Dirk Haller (Tekijä), Silke Kiessling (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: Elsevier, 2022-12-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Objective: Internal clocks time behavior and physiology, including the gut microbiome, in a circadian (∼24 h) manner. Mismatch between internal and external time, e.g. during shift work, disrupts circadian system coordination promoting the development of obesity and type 2 diabetes (T2D). Conversely...