Design, synthesis, α-glucosidase inhibition and hypoglycemic activity of 3-aceto(benzo)hydrazide-1,2,4-triazines as potential anti-diabetic agents

• Egile Nagusiak: Mehdi Valipour (Egilea), Zahra Zakeri (Egilea), Kaveh Kiadaliry (Egilea), Somayeh Mojtabavi (Egilea), Mohammad Ali Faramarzi (Egilea), Mohammad Shokati Sayyad (Egilea), Mohammad Seyedabadi (Egilea), Majid Ghasemian (Egilea), Seyedeh Mahdieh Hashemi (Egilea), Hamid Irannejad (Egilea)
• Formatua: Liburua
• Argitaratua: Elsevier, 2024-12-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Type 2 diabetes is a common condition that causes the level of glucose in the blood to become too high and α-glucosidase inhibitors are therapeutic agents in managing type 2 diabetes. In the present study, we report a new series of 3-aceto(benzo)hydrazide-1,2,4-triazine analogs as potential therapeu...