Effects of the European restrictive actions concerning nimesulide prescription: a simulation study on hepatopathies and gastrointestinal bleedings in Italy

• Autors principals: Mauro Venegoni (Autor), Roberto Da Cas (Autor), Francesca Menniti-Ippolito (Autor), Giuseppe Traversa (Autor)
• Format: Llibre
• Publicat: Istituto Superiore di Sanità, 2010-06-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

In 2002 and 2007 the European Medicines Agency (EMA) examined the signals of a greater risk of hepatopathies related to nimesulide use. In 2007 restrictive actions were adopted in Europe. Moreover, EMA initiated a new referral in February 2010. The objective of this paper is to evaluate the effects...