Quercetin Disaggregates Prion Fibrils and Decreases Fibril-Induced Cytotoxicity and Oxidative Stress

Transmissible spongiform encephalopathies (TSEs) are fatal neurodegenerative diseases caused by misfolding and aggregation of prion protein (PrP). Previous studies have demonstrated that quercetin can disaggregate some amyloid fibrils, such as amyloid β peptide (Aβ) and α-synuclein. However, the dis...

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Main Authors: Kun-Hua Yu (Author), Cheng-I Lee (Author)
Format: Book
Published: MDPI AG, 2020-11-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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