Role of IKKε in the Metabolic Diseases: Physiology, Pathophysiology, and Pharmacology

• Main Authors: Qing-Ao Xiao (Author), Qian He (Author), Lun Li (Author), Yinhong Song (Author), Yue-ran Chen (Author), Jun Zeng (Author), Xuan Xia (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

IKKε (inhibitor of nuclear factor kappa-B kinase ε) is a member of the noncanonical NF-κB pathway. It participates in the inflammatory response and innate immunity against bacteria. In recent decades, IKKε has been closely associated with metabolic regulation. Inhibition of the IKKε pathway can impr...