Adhesion between EVs and tumor cells facilitated EV-encapsulated doxorubicin delivery via ICAM1

• Main Authors: Shibo Wang (Author), Chenxiao Qiao (Author), Xianghui Kong (Author), Jie Yang (Author), Fei Guo (Author), Jiming Chen (Author), Wenhui Wang (Author), Bei Zhang (Author), Huiqing Xiu (Author), Yuzhou He (Author), Jianli Wang (Author), Huajun Feng (Author), Zhijian Cai (Author)
• Format: Book
• Published: Elsevier, 2024-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Doxorubicin (Dox) is an anti-tumor drug with a broad spectrum, whereas the cardiotoxicity limits its further application. In clinical settings, liposome delivery vehicles are used to reduce Dox cardiotoxicity. Here, we substitute extracellular vesicles (EVs) for liposomes and deeply investigate the...