STAT3-mediated up-regulation of DAB2 via SRC-YAP1 signaling axis promotes Helicobacter pylori-driven gastric tumorigenesis

• Main Authors: Yantao Duan (Author), Pengfei Kong (Author), Mingzhu Huang (Author), Yonghao Yan (Author), Yi Dou (Author), Binhao Huang (Author), Jing Guo (Author), Wei Kang (Author), Caixia Zhu (Author), Yuyan Wang (Author), Donglei Zhou (Author), Qiliang Cai (Author), Dazhi Xu (Author)
• Format: Book
• Published: BMC, 2024-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Helicobacter pylori (H pylori) infection is the primary cause of gastric cancer (GC). The role of Disabled-2 (DAB2) in GC remains largely unclear. This study aimed to investigate the role of DAB2 in H pylori-mediated gastric tumorigenesis. Methods We screened various datasets of...