Netosis and Inflammasomes in Large Vessel Occlusion Thrombi

• Main Authors: Stephanie H. Chen (Author), Xavier O. Scott (Author), Yoandy Ferrer Marcelo (Author), Vania W. Almeida (Author), Patricia L. Blackwelder (Author), Dileep R. Yavagal (Author), Eric C. Peterson (Author), Robert M. Starke (Author), W. Dalton Dietrich (Author), Robert W. Keane (Author), Juan Pablo de Rivero Vaccari (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The inflammatory response appears to play a critical role in clotting in which neutrophil extracellular traps (NETs) are the major drivers of thrombosis in acute ischemic stroke (AIS). The inflammasome is an innate immune complex involved in the activation of interleukin (IL)-18 and IL-1β through ca...