Adjuvant DNA vaccine pNMM promotes enhanced specific immunity and anti-tumor effects

• Main Authors: Yu Wang (Author), Weiwei Song (Author), Qiang Xu (Author), Yachao Liu (Author), Hezhong Liu (Author), Runzi Guo (Author), Chuang-Jiun Chiou (Author), Kun Gao (Author), Baofeng Jin (Author), Changfeng Chen (Author), Zhongming Li (Author), Jinqi Yan (Author), Jiyun Yu (Author)
• Format: Book
• Published: Taylor & Francis Group, 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

DNA vaccines containing only antigenic components have limited efficacy and may fail to induce effective immune responses. Consequently, adjuvant molecules are often added to enhance immunogenicity. In this study, we generated a tumor vaccine using a plasmid encoding NMM (NY-ESO-1/MAGE-A3/MUC1) targ...