Altered DNA methylation in liver and adipose tissues derived from individuals with obesity and type 2 diabetes

• Päätekijät: Francisco Barajas-Olmos (Tekijä), Federico Centeno-Cruz (Tekijä), Carlos Zerrweck (Tekijä), Iván Imaz-Rosshandler (Tekijä), Angélica Martínez-Hernández (Tekijä), Emilio J. Cordova (Tekijä), Claudia Rangel-Escareño (Tekijä), Faustino Gálvez (Tekijä), Armando Castillo (Tekijä), Hernán Maydón (Tekijä), Francisco Campos (Tekijä), Diana Gabriela Maldonado-Pintado (Tekijä), Lorena Orozco (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: BMC, 2018-02-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Abstract Background Obesity is a well-recognized risk factor for insulin resistance and type 2 diabetes (T2D), although the precise mechanisms underlying the relationship remain unknown. In this study we identified alterations of DNA methylation influencing T2D pathogenesis, in subcutaneous and visc...