Altered DNA methylation in liver and adipose tissues derived from individuals with obesity and type 2 diabetes

• मुख्य लेखकों: Francisco Barajas-Olmos (लेखक), Federico Centeno-Cruz (लेखक), Carlos Zerrweck (लेखक), Iván Imaz-Rosshandler (लेखक), Angélica Martínez-Hernández (लेखक), Emilio J. Cordova (लेखक), Claudia Rangel-Escareño (लेखक), Faustino Gálvez (लेखक), Armando Castillo (लेखक), Hernán Maydón (लेखक), Francisco Campos (लेखक), Diana Gabriela Maldonado-Pintado (लेखक), Lorena Orozco (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: BMC, 2018-02-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Abstract Background Obesity is a well-recognized risk factor for insulin resistance and type 2 diabetes (T2D), although the precise mechanisms underlying the relationship remain unknown. In this study we identified alterations of DNA methylation influencing T2D pathogenesis, in subcutaneous and visc...