Brain Delivery of a Potent Opioid Receptor Agonist, Biphalin during Ischemic Stroke: Role of Organic Anion Transporting Polypeptide (OATP)

• Main Authors: Thamer H Albekairi (Author), Bhuvaneshwar Vaidya (Author), Ronak Patel (Author), Saeideh Nozohouri (Author), Heidi Villalba (Author), Yong Zhang (Author), Yeon Sun Lee (Author), Abraham Al-Ahmad (Author), Thomas J Abbruscato (Author)
• Format: Book
• Published: MDPI AG, 2019-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Transporters (expressed) at the blood-brain barrier (BBB) can play an essential role in the treatment of brain injury by transporting neuroprotective substance to the central nervous system. The goal of this study was to understand the role of organic anion transporting polypeptide (OATP1; OATP1A2 i...