Downregulation of HMGA2 by Small Interfering RNA Affects the Survival, Migration, and Apoptosis of Prostate Cancer Cell Line

• Main Authors: Shima Khajouee (Author), Elham Baghbani (Author), Ali Mohammadi (Author), Behzad Mansoori (Author), Dariush Shanehbandi (Author), Khalil Hajiasgharzadeh (Author), Behzad Baradaran (Author)
• Format: Book
• Published: Tabriz University of Medical Sciences, 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Purpose: To investigate the downregulation of high mobility group AT-hook 2 (HMGA2)expression by small interfering RNAs (siRNAs) in PC3 prostate cancer cell line. HMGA2belongs to the non-histone chromatin-binding protein family that serves as a crucial regulator ofgene transcription. The overexpress...