Downregulation of HMGA2 by Small Interfering RNA Affects the Survival, Migration, and Apoptosis of Prostate Cancer Cell Line

• Autors principals: Shima Khajouee (Autor), Elham Baghbani (Autor), Ali Mohammadi (Autor), Behzad Mansoori (Autor), Dariush Shanehbandi (Autor), Khalil Hajiasgharzadeh (Autor), Behzad Baradaran (Autor)
• Format: Llibre
• Publicat: Tabriz University of Medical Sciences, 2022-03-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

Purpose: To investigate the downregulation of high mobility group AT-hook 2 (HMGA2)expression by small interfering RNAs (siRNAs) in PC3 prostate cancer cell line. HMGA2belongs to the non-histone chromatin-binding protein family that serves as a crucial regulator ofgene transcription. The overexpress...