Inhibitors of DNA Methyltransferases From Natural Sources: A Computational Perspective

• Main Authors: Fernanda I. Saldívar-González (Author), Alejandro Gómez-García (Author), David E. Chávez-Ponce de León (Author), Norberto Sánchez-Cruz (Author), Javier Ruiz-Rios (Author), B. Angélica Pilón-Jiménez (Author), José L. Medina-Franco (Author)
• Format: Book
• Published: Frontiers Media S.A., 2018-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Naturally occurring small molecules include a large variety of natural products from different sources that have confirmed activity against epigenetic targets. In this work we review chemoinformatic, molecular modeling, and other computational approaches that have been used to uncover natural produc...