Dual Role of PTPN22 but Not NLRP3 Inflammasome Polymorphisms in Type 1 Diabetes and Celiac Disease in Children

• Main Authors: Darja Smigoc Schweiger (Author), Katja Goricar (Author), Tinka Hovnik (Author), Andrijana Mendez (Author), Natasa Bratina (Author), Jernej Brecelj (Author), Blanka Vidan-Jeras (Author), Tadej Battelino (Author), Vita Dolzan (Author)
• Format: Book
• Published: Frontiers Media S.A., 2019-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Genetic polymorphisms in genes coding for inflammasome components nucleotide-binding oligomerization domain leucine rich repeat and pyrin domain-containing protein 3 (NLRP3) and caspase recruitment domain-containing protein 8 (CARD8) have been associated with autoinflammatory and autoimmune diseases...