A Murine Model of Enterohemorrhagic Escherichia coli O157:H7 Infection to Assess Immunopotentiating Activity of Drugs on Mucosal Immunity: Effect of Drugs

• Main Authors: Keiji Nagano (Author), Takeshi Sugisaki (Author), Kazuki Taguchi (Author), Takumi Hara (Author), Mitsuru Naiki (Author), Hiroshi Mori (Author)
• Format: Book
• Published: Elsevier, 2003-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

An enterohemorrhagic Escherichia coli (EHEC) O157 oral infection murine model was established to examine the potentiating activity of drugs on mucosal immune responses. Groups of ICR mice inoculated intragastrically with 1011 CFU/kg EHEC O157 showed chronic intestinal infection with the pathogen tha...