Modulation of ambient temperature promotes inflammation and initiates atherosclerosis in wild type C57BL/6 mice

• Main Authors: Daniel A. Giles (Author), Bhama Ramkhelawon (Author), Elizabeth M. Donelan (Author), Traci E. Stankiewicz (Author), Susan B. Hutchison (Author), Rajib Mukherjee (Author), Monica Cappelletti (Author), Rebekah Karns (Author), Christopher L. Karp (Author), Kathryn J. Moore (Author), Senad Divanovic (Author)
• Format: Book
• Published: Elsevier, 2016-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objectives: Obesity and obesity-associated inflammation is central to a variety of end-organ sequelae including atherosclerosis, a leading cause of death worldwide. Although mouse models have provided important insights into the immunopathogenesis of various diseases, modeling atherosclerosis in mic...