Use of recombinant human deoxyribonuclease in pediatric intensive care unit - a single-center experience

• Main Authors: Daniel Meireles (Author), Sofia Ribeiro Fernandes (Author), Alzira Sarmento (Author), Telma Barbosa (Author), Manuel Ferreira Magalhães (Author), Ana Ramos (Author), Paula Cristina Fernandes (Author)
• Format: Book
• Published: Sociedade de Pediatria de São Paulo, 2021-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

ABSTRACT Objective: Dornase alfa (rhDNase) reduces the viscosity of purulent sputum in the lungs. The use in patients with cystic fibrosis (CF) is proven. However, the evidence of its applicability to other conditions is limited. This study aims to present the authors' experience with the use o...