TLR-mediated albuminuria needs TNFα-mediated cooperativity between TLRs present in hematopoietic tissues and CD80 present on non-hematopoietic tissues in mice

• Main Authors: Nidhi Jain (Author), Bhavya Khullar (Author), Neelam Oswal (Author), Balaji Banoth (Author), Prashant Joshi (Author), Balachandran Ravindran (Author), Subrat Panda (Author), Soumen Basak (Author), Anna George (Author), Satyajit Rath (Author), Vineeta Bal (Author), Shailaja Sopory (Author)
• Format: Book
• Published: The Company of Biologists, 2016-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Transient albuminuria induced by pathogen-associated molecular patterns (PAMPs) in mice through engagement of Toll-like receptors (TLRs) is widely studied as a partial model for some forms of human nephrotic syndrome (NS). In addition to TLRs, CD80 has been shown to be essential for PAMP-mediated al...