Up-Down Reader: An Open Source Program for Efficiently Processing 50% von Frey Thresholds

• Main Authors: Rafael Gonzalez-Cano (Author), Bruno Boivin (Author), Daniel Bullock (Author), Laura Cornelissen (Author), Nick Andrews (Author), Michael Costigan (Author)
• Format: Book
• Published: Frontiers Media S.A., 2018-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Most pathological pain conditions in patients and rodent pain models result in marked alterations in mechanosensation and the gold standard way to measure this is by use of von Frey fibers. These graded monofilaments are used to gauge the level of stimulus-evoked sensitivity present in the affected...